REVIEW ARTIKEL: KAJIAN ETNOBOTANI, FITOKIMIA, DAN AKTIVITAS FARMAKOLOGI FAMILY PANDANACEAE

Nadiya Nadiya, Dhea Olga Kharina, Nadila Ambar Sari, Septriyanto Dirgantara

Abstrak


Genus Pandanus dan Sararanga merupakan anggota penting dari famili Pandanaceae yang banyak ditemukan di wilayah tropis, terutama Indonesia bagian timur seperti Papua dan Maluku. Tumbuhan dari kedua genus ini telah lama dimanfaatkan oleh masyarakat setempat sebagai bahan pangan, obat tradisional, dan dalam praktik budaya lokal. Studi ini bertujuan untuk meninjau potensi farmakologi dan kandungan senyawa aktif dari beberapa spesies utama seperti Pandanus amaryllifolius, Pandanus tectorius, Pandanus conoideus, Pandanus julianettii, dan Sararanga sinuosa. Metode yang digunakan adalah telaah literatur dari jurnal nasional dan internasional yang diperoleh melalui DOAJ, Google Scholar, PubMed, dan ScienceDirect. Dari total 105 jurnal yang ditemukan, sebanyak 42 jurnal yang relevan digunakan dalam analisis akhir. Hasil telaah menunjukkan bahwa genus ini memiliki beragam aktivitas farmakologi seperti antioksidan, antidiabetik, antiinflamasi, antivirus, antibakteri, antiglikasi, dan hipolipidemik. Senyawa bioaktif yang telah diisolasi meliputi flavonoid, alkaloid, tanin, saponin, triterpenoid, steroid, fenolat, dan karotenoid. Khususnya, Pandanus julianettii dan Sararanga sinuosa menunjukkan potensi farmakologis yang menjanjikan, namun masih terbatas bukti ilmiahnya. Oleh karena itu, diperlukan penelitian lebih lanjut yang mendalam dan terstandar untuk mengeksplorasi manfaat terapeutik dari kedua spesies tersebut secara lebih komprehensif.

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Referensi


Ambarwati, N. S. S., Sukma, N. T., Yesi Desmiaty, A. A., Setia Budi, M. A., & Ahmad, I. (2024). Antihypercholesterolemic and antiatherosclerotic potencies of Pandanus tectorius fruits via increasing scavenger receptor-B1 genes expression and inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity. Journal of Advanced Pharmaceutical Technology & Research, 15(1), 8–12. https://doi.org/10.4103/japtr.japtr

Andriani, Y., Ramli, N. M., Musa, N. S., Kanwal, K., Mohamad, H., Amir, H., Kassim, M. N. I., Syamsumir, D. F., Muhammad, T. S. T., & Assaw, S. (2022). Anti-inflammatory activity of phenolic-rich fraction of Pandanus tectorius fruits via reduction of NO production on lipopolysaccharide-stimulated RAW264.7 cell lines and formalin-induced paw Oedema. Thai Journal of Pharmaceutical Sciences, 46(5), 551–560. https://doi.org/10.56808/3027-7922.2639

Andriani, Y., Ramli, N. M., Syamsumir, D. F., Kassim, M. N. I., Jaafar, J., Aziz, N. A., Marlina, L., Musa, N. S., & Mohamad, H. (2019). Phytochemical analysis, antioxidant, antibacterial and cytotoxicity properties of keys and cores part of Pandanus tectorius fruits. Arabian Journal of Chemistry, 12(8), 3555–3564. https://doi.org/10.1016/j.arabjc.2015.11.003

Antonius, D. M., Marissa, D., Juniarti, L., Kartika, N., Nurmanisari, & Pratiwi, E. (2021). Uji Kualitatif Fitokimia Daun Pandan. Jurnal Kimia Organik, 2(1), 1–12. https://www.researchgate.net/publication/348756877

Asrianto, A., Purwati, R., Setiani, D., Asrori, Taufik Sahli, I., & Hartati, R. (2023). Skrining dan Bioaktivitas Ekstrak Buah Merah (Pandanus conoideus Lamk.) Asal Kabupaten Pegunungan Bintang terhadap Jamur Candida Albicans: Penelitian Randomisasi. Health Information : Jurnal Penelitian, 15(1), 12–22. https://doi.org/10.36990/hijp.v15i1.721

Astari, J. I. R., Anam, K., Aminin, A. L. N., & Rahma, F. F. (2024). HMG-CoA Reductase Inhibition Activity of Sea Pandan Leaves (P. tectorius). Tropical Journal of Natural Product Research, 8(4), 6975–6980. https://doi.org/10.26538/tjnpr/v8i4.31

Baba, S., Chan, H. T., Kezuka, M., Inoue, T., & Chan, E. W. C. (2016). Artocarpus altilis and Pandanus tectorius: Two important fruits of Oceania with medicinal values. Emirates Journal of Food and Agriculture, 28(8), 531–539. https://doi.org/10.9755/ejfa.2016-02-207

Chiabchalard, A., & Nooron, N. (2015). Antihyperglycemic effects of Pandanus amaryllifolius Roxb. leaf extract. Pharmacognosy Magazine, 11(41), 117–122. https://doi.org/10.4103/0973-1296.149724

Condro, N. (2020). Skrinning Fitokimia Pandanus julianetii Sebagai Sumber Pangan Fungsional Lokal Papua. Jurnal Ilmu Pangan Dan Hasil Pertanian, 4(1), 74–82. https://doi.org/10.26877/jiphp.v4i1.6182

del Mundo, C. R., Castillo, A. L., An, S. S. A., & Tan, M. A. (2020). In vivo COX-2 modulation and metabolite profiling of Pandanus tectorius leaves extracts. 3 Biotech, 10(3), 1–10. https://doi.org/10.1007/s13205-020-2087-8

Dianingsih, N., Zebua, L. I., Purnamasari, V., & Suyono, I. J. (2024). Fatty acid composition of two new pandanus oil from Lanny Jaya District, Papua: Pandanus iwen and Pandanus jiulianettii seed oil. BIO Web of Conferences, 123. https://doi.org/10.1051/bioconf/202412302006

Ghasemzadeh, A., & Jaafar, H. Z. E. (2014). Optimization of reflux conditions for total flavonoid and total phenolic extraction and enhanced antioxidant capacity in pandan (Pandanus amaryllifolius Roxb.) using response surface methodology. The Scientific World Journal, 2014(1), 523120.

Heriyanto, Gunawan, I. A., Fujii, R., Maoka, T., Shioi, Y., Kameubun, K. M. B., Limantara, L., & Brotosudarmo, T. H. P. (2021). Carotenoid composition in buah merah (Pandanus conoideus Lam.), an indigenous red fruit of the Papua Islands. In Journal of Food Composition and Analysis (Vol. 96). Elsevier Inc. https://doi.org/10.1016/j.jfca.2020.103722

Husein Wawo, A., Lestari, P., & Setyowati, N. (2019). Buah Merah (Pandanus conoideus Lamk) Bioresources Pegunungan Tengah Papua: Keanekaragaman dan Upaya Konservasinya. Jurnal Biologi Indonesia, 15(1), 107–121. https://doi.org/10.47349/jbi/15012019/107

Khairani, A. C., & Indriani, N. (2024). Identifikasi Kandungan Senyawa Fitokimia Minyak Buah Merah ( Pandanus conoideus Lam .) Identification Of Phytochemical Compound Content of Red Fruit Oil ( Pandanus conoideus Lam .). 7(12), 4599–4603. https://doi.org/10.56338/jks.v7i12.6335

Khairani, A. C., Tri Wijayanti, & Gunawan Pamudji Widodo. (2023). Antihyperglycemic Activity of Red Fruit Oil (Pandanus conoideus Lam) on Improving Kidney Function in STZ- NA-Induced Nephropathy Rats. Jurnal Farmasi Dan Ilmu Kefarmasian Indonesia, 10(2), 173–183. https://doi.org/10.20473/jfiki.v10i22023.173-183

Laluces, H. M. C., Nakayama, A., Nonato, M. G., dela Cruz, T. E., & Tan, M. A. (2015). Antimicrobial alkaloids from the leaves of Pandanus amaryllifolius. Journal of Applied Pharmaceutical Science, 5(10), 151–153. https://doi.org/10.7324/JAPS.2015.501026

Mai, D. T., Le, T. D., Nguyen, T. P., Phan, N. M., Nguyen, H. A., Nguyen, T. T. P., & Tran, L. Q. (2015). A new aldehyde compound from the fruit of Pandanus tectorius Parkinson ex du Roi. Natural Product Research, 29(15), 1437–1441. https://doi.org/10.1080/14786419.2014.1003929

Migau, N., Mokosuli, Y., Wurarah, M., & Manampiring, N. (2024). The Antioxidant Activity of Red Fruit Extract (Pandanus conoideus L.) From Nabire Papua. Indonesian Biodiversity Journal, 5(1), 52–58. https://doi.org/10.53682/ibj.v5i1.9174

Nawawi, A. (2015). SERBUK PANDAN WANGI (Pandanus amaryllifolius Roxb.) DAN PEMANFAATANNYA SEBAGAI PENAMBAH AROMA PADA MAKANAN. Jurnal Kesehatan Bakti Tunas Husada: Jurnal Ilmu-Ilmu Keperawatan, Analis Kesehatan Dan Farmasi, 11(1), 114. https://doi.org/10.36465/jkbth.v11i1.51

Nurfadila, N., Iqbal, M., & Pitopang, R. (2019). Kajian Etnobotani Pandanaceae Pada Suku Moma Di Ngata Toro, Kulawi, Sulawesi Tengah. Natural Science: Journal of Science and Technology, 8(1), 36–43. https://doi.org/10.22487/25411969.2019.v8.i1.12634

Ooi, L. S. M., Sun, S. S. M., & Ooi, V. E. C. (2004). Purification and characterization of a new antiviral protein from the leaves of Pandanus amaryllifolius (Pandanaceae). International Journal of Biochemistry and Cell Biology, 36(8), 1440–1446. https://doi.org/10.1016/j.biocel.2004.01.015

Pigai, H., Simaremare, E. S., Mangiwa, S., & Rysbekova, A. (2024). Assessment Of Free Radical In Ethyl Acetate Extract Of Pandanus Julianettii Fruit Using The DPPH Method. 2(2), 237–247. https://doi.org/10.5281/zenodo.10648709

Purnamasari, V., Estiasih, T., Sujuti, H., & Widjanarko, S. B. (2021). Identification of phenolic acids of Pandan anggur (Sararanga sinuosa Hemsley) fruits and their potential antiglycation through molecular docking study. Journal of Applied Pharmaceutical Science, 11(2), 126–134. https://doi.org/10.7324/JAPS.2021.110216

Purwanto, Y., & Munawaroh, E. (2010). Etnomotani Jenis-Jenis Pandanaceae Sebagai Bahan Pangan di Indonesia. Hayati Edisi Khusus, 5(1), 97–108.

Quyen, N. T. C., Quyen, N. T. N., Nhan, L. T. H., & Toan, T. Q. (2020). Antioxidant activity, total phenolics and flavonoids contents of Pandanus amaryllifolius (Roxb.). IOP Conference Series: Materials Science and Engineering, 991(1). https://doi.org/10.1088/1757-899X/991/1/012019

Rosidah, . (2021). A Mini-Review: Effect of Pandanus amaryllifolius Roxb Leaves for Fish Health. Asian Journal of Fisheries and Aquatic Research, 12(3), 31–41. https://doi.org/10.9734/ajfar/2021/v12i330236

Sa’adah, S. M., Putri, F. R., Ibtisam, A. A., Arrohmah, R. S., & Fitriyah, F. (2023). Phytochemical analysis of secondary metabolite compounds of Pandanwangi leaf extract (Pandanus amaryllifolius). Journal of Natural Sciences and Mathematics Research, 9(2), 135–142. https://doi.org/10.21580/jnsmr.2023.9.2.16421

Sarungallo, Z. L., Murtiningrum, Uhi, H. T., Roreng, M. K., & Pongsibidang, A. (2014). The Organoleptic Properties, Physical Properties, and the Level of β-carotene and α-tocopherol of Red Fruit (Pandanus conoideus) Oil Emulsion. Agritech, 34(2), 177–183.

Secretariat, G. (2025). Pandanaceae R.Br. in GBIF Backbone Taxonomy. https://www.gbif.org/species/3737.

Sianipar, F. R. D. N. (2016). Morphological And Anatomical Structure Of Red Fruit (Pandanus Conoideus Lam.). KnE Social Sciences, 1(1), 37–43. https://doi.org/10.18502/kss.v1i1.432

Sundari, I., & Wibowo, F. R. (2015). Identifikasi Senyawa dalam Ekstrak Etanol Biji Buah Merah (Pandanus conoideus). Biofarmasi, 13(2), 78–89. https://doi.org/10.13057/biofar/f130205

Tian, Y., Cao, X. X., Shang, H., Wu, C. M., Zhang, X., Guo, P., Zhang, X. P., & Xu, X. D. (2019). Synthesis and in vitro evaluation of caffeoylquinic acid derivatives as potential hypolipidemic agents. Molecules, 24(5), 1–11. https://doi.org/10.3390/molecules24050964

Umar, A. K. (2021). Flavonoid compounds of buah merah (Pandanus conoideus Lamk) as a potent SARS-CoV-2 main protease inhibitor: in silico approach. Future Journal of Pharmaceutical Sciences, 7(1), 0–8. https://doi.org/10.1186/s43094-021-00309-0

Wabula, R. A., Dali, S., & Widiastuti, H. (2019). Aktivitas Antioksidan Ekstrak Etanol Buah Merah (Pandanus conoideus Lam.) dengan Metode FRAP. Window of Health : Jurnal Kesehatan, 2(4), 329–337. https://doi.org/10.33368/woh.v0i0.203

Widiatmika, K. P. (2015). ANALISIS KADAR TOTAL FENOL PADA MINYAK DAN SARI BUAH MERAH (PANDANUS CONOIDEUS). Jurnal Crystal: Publikasi Penelitian Kimia Dan Terapannya, 6 (1)(2), 25–32. https://doi.org/https://doi.org/10.36526/jc.v6i1.3590

Wu, C., Luan, H., Wang, S., Zhang, X., Liu, H., & Guo, P. (2015). [Pandanus tectorius derived caffeoylquinic acids inhibit lipid accumulation in HepG2 hepatoma cells through regulation of gene expression involved in lipid metabolism]. Yao Xue Xue Bao = Acta Pharmaceutica Sinica, 50(3), 278—283. http://europepmc.org/abstract/MED/26118105

Zebua, L. I. (2015). PEMANFAATAN PANDAN-PANDANAN (Pandanaceae) OLEH MASYARAKAT PAPUA. Novae Guinea Jurnal Biologi, 6(2).

Zhang, X., Wu, C., Wu, H., Sheng, L., Su, Y., Zhang, X., Luan, H., Sun, G., Sun, X., Tian, Y., Ji, Y., Guo, P., & Xu, X. (2013). Anti-Hyperlipidemic Effects and Potential Mechanisms of Action of the Caffeoylquinic Acid-Rich Pandanus tectorius Fruit Extract in Hamsters Fed a High Fat-Diet. PLoS ONE, 8(4). https://doi.org/10.1371/journal.pone.0061922




DOI: https://doi.org/10.24198/farmaka.v23i3.65980

DOI (PDF): https://doi.org/10.24198/farmaka.v23i3.65980.g27019

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