Sistem Penghantaran Obat Ekstrak Herbal dalam Formulasi dan Aplikasi Biomedis

Rizqa Nurul Aulia, Sriwidodo Sriwidodo

Abstrak

Penggunaan bahan alam dalam dunia kesehatan telah banyak dipilih secara turun temurun untuk menangani berbagai macam masalah kesehatan. Namun penggunaan tanaman sebagai zat aktif dalam formulasi obat masih memiliki banyak keterbatasan terutama dalam kelarutan dan biovailibilitas dalam tubuh. Sehingga untuk mengatasi hal tersebut, penelitian terkait sistem penghantaran obat herbal terus dikembangkan dengan tujuan untuk membuat formulasi terbaik dan tercapainya efektivitas terapi dari obat herbal. Sistem penghantaran baru obat herbal antara lain meliputi sistem penghantaran vesikular seperti liposom, fitosom, etosom, transferosom, sistem penghantaran partikulat seperti mikrosfer, mikropellet, nanopartikel, dan emulsi mikro dan nano. Penggunaan sistem penghantaran obat tersebut bertujuan meningkatkan stabilitas, ketersediaan hayati dan pengurangan toksisitas. Tinjauan ini menyoroti status perkembangan formulasi herbal baru dan aplikasinya dalam terapi.

Kata Kunci : Sistem penghantaran obat, obat herbal, aplikasi biomedik

Kata Kunci

Sistem penghantaran obat, obat herbal, aplikasi biomedik

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Daftar Pustaka

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DOI: https://doi.org/10.24198/mfarmasetika.v7i5.39613

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