Analisis Minimalisasi Biaya Terapi Antihipertensi dengan Kaptopril-Hidroklorotiazid dan Amlodipin-Hidroklorotiazid di Salah Satu Rumah Sakit Kota Bandung

Andini Faramitha, Budhi Prihartanto, Dika P. Destiani

Abstract


Keberhasilan terapi hipertensi stage 2 dapat ditunjang dengan adanya pemberian antihipertensi. Beragamnya alternatif terapi antihipertensi menjadikan studi farmakoekonomi diperlukan agar diperoleh terapi yang efektif dan efisien. Tujuan penelitian ini adalah untuk mencari kelompok kombinasi antihipertensi yang lebih efisien dalam hal biaya (minimalisasi biaya) yang digunakan pada pasien hipertensi stage 2 yang dirawat di salah satu rumah sakit swasta Kota Bandung periode tahun 2011–2013. Penelitian ini merupakan studi observasional dengan pengumpulan data secara retrospektif. Pengambilan data dilakukan dengan mengambil rekam medis pasien rawat inap hipertensi stage 2 dan mendapat terapi antihipertensi kaptopril-hidroklorotiazid dan amlodipin-hidroklorotiazid. Komponen biaya yang dikumpulkan meliputi biaya antihipertensi, biaya tindakan, biaya penunjang, biaya rawat inap dan biaya administrasi. Hasil penelitian menunjukkan bahwa total biaya perawatan kombinasi antihipertensi kaptopril-hidroklorotiazid lebih rendah dibandingkan amlodipin-hidroklorotiazid, dengan selisih sebesar Rp126.798.

Kata kunci: Antihipertensi, biaya minimal, farmakoekonomi, hipertensi


Cost Minimization Analysis of Antihypertensive Therapy with Captopril-Hydrochlorothiazide and Amlodipine-Hydrochlorothiazide in One of Hospitals in Bandung

The successful therapy of stage 2 hypertension  can be supported by the administration of antihypertensive. Existence of various antihypertensive alternative making pharmacoeconomics study is needed in order to have an effective and efficient therapy. Purpose of this study was to find the antihypertensive group therapy which is more efficient in cost (cost minimization) which used in the treatment of stage 2 hypertension in patients at one hospital in Bandung from 2011 until 2013. This study is an observational reserach with retrospective data collection. Data retrieval was done by taking the medical records of hospitalized patients who received therapy of stage 2 hypertension antihypertensive, captopril-hydrochlorothiazide or amlodipin-hydrochlorothiazide. Components that were collected includes the cost of antihypertensive, supportive therapy costs, the cost of action, administrative expenses and cost of hospitalization. The result of this study of cost minimization analysis showed that the total cost of treatment with the antihypertensive captopril-hydrochlorothiazide is lower compared to amlodipin- hydrochlorothiazide, with the difference amounting to Rp126,798.

Keywords: Antihypertensive, cost minimization, pharmacoeconomy, hypertension


Keywords


Antihipertensi, biaya minimal, farmakoekonomi, hipertensi

References


Badan Penelitian dan Pengembangan Kesehatan Departemen Kesehatan Republik Indonesia. Operational study an integrated community-based intervention program on common risk factors of major non-communicable diseases in Depok-Indonesia (riset). Jakarta: Departemen Kesehatan Republik Indonesia; 2006.

Indian Guidelines on hypertension (I.G.H) -III. J Assoc Physicians India. 2013;61(2):6–36.

World Health Organization (WHO) and International Society of Hypertension (ISH). Statement of management of hypertension. J Hypertens. 2003;21:1983–92.

World Health Organization (WHO). The world health report: Reducing risk, promoting healthy life. Geneva: World Health Organization [diunduh 16 juli 2015]. Tersedia dari: http://www.who.int/entity/whr/2002/en/whr02_en.pdf

Yang H, Schnall PL, Jauregui M, Su TC, Baker D. Work hours and self-reported hypertension among working people in California. Hypertension. 2006;48(4):744–50. doi: 10.1161/01.HYP.0000238327.41911.52

Departemen Kesehatan Republik Indonesia. Riset kesehatan dasar Indonesia. Jakarta: Departemen Kesehatan Republik Indonesia; 2007.

Wang TJ, Vasan RS. Epidemiology of uncontrolled hypertension in the United States. Circulation. 2005;112(11):1651–62. doi: 10.1161/CIRCULATIONAHA.104.490599

Sugiharto A. Faktor-faktor risiko hipertensi grade II pada masyarakat (tesis). Semarang: Universitas Diponegoro; 2006.

Eshiet UI, Yusuff KB. Anti-hypertensive medicines prescribing for medical outpatients in a premier teaching hospital in Nigeria: A probable shift of pardigm. Pharm Pract. 2014;12(2):419.

Dragomir A, Côté R, Roy L, Blais L, Lalonde L, Bérard A, et al. Impact of adherence to antihypertensive agents on clinical outcomes and hospitalization costs. Med Care. 2010:48(5):418-25. doi: 10.1097/MLR.0b013e3181d567bd.

Goldman MP, Nair R. Antibacterial treatment strategies in hospitalized patient: what role for pharmacoeconomics. Clev Clin J Med. 2007;74(4):s38–s47. doi: 10.3949/ccjm.74.Suppl_4.S38

Pane AH. Re-profesionalisasi farmasis. Makalah seminar regional pharmaceutical care: Idealisme versus realita. Jakarta: IPHW; 2003.

Vogenberg FR. Introduction to applied pharmacoeconomics. New York: The McGraw-Hill Companies Inc; 2001.

James PA, Oparil S, Carter BL, Cushman WC, Dennison-Himmelfarb C, Handler J, et al. 2014 evidence-based guideline for the management of high blood pressure in adults: Report from the panel members appointed to the Eighth Joint National Committee (JNC 8). J Am Med Assoc. 2014;311(5):507–20. doi: 10.1001/jama.2013.284427

Windiari R. Evaluasi penggunaan obat antihipertensi ditinjau dari perspektif biaya dan keefektifan terapi di UPT Yankes Bumi Medika Ganesha Bandung (skripsi). Bandung: Institut Teknologi Bandung; 2014.

Departemen Kesehatan Republik Indonesia. Pedoman tatalaksana gizi usia lanjut untuk tenaga kesehatan. Jakarta: Direktorat Bina Gizi Mayarakat Ditjen Binkesmas Departemen Kesehatan Republik Indonesia; 2006.

Yanes LL, Reckelhoff JF. Postmenopausal hypertension. Am J Hypertens. 2011;24(7):740–9. doi: 10.1038/ajh.2011.71

Kumar V, Abbas AK, Fausto N. Hypertensive vascular disease. In: Robn and Cotran pathologic basis of disease, 7th edition. Philadelpia: Elsevier Saunders; 2005.

Zuraidah, Maksuk, Apriliadi N. Analisis faktor risiko penyakit hipertensi pada masyarakat di Kecamatan Kemuning Kota Palembang tahun 2012 [diunduh 16 Maret 2015]. Tersedia dari: http://poltekkespalembang.ac.id/userfilesfiles/analisis_faktor_risiko_penyakithipertens i_pada_masyarakat_di_kecamatankemu ning_ kota_palembang_tahun_2012.pdf




DOI: https://doi.org/10.15416/ijcp.2017.6.3.220

Refbacks

  • There are currently no refbacks.


 Indonesian Journal of Clinical Pharmacy is indexed by

        

  Creative Commons License

IJCP by Universitas Padjadjaran is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License

 

View My Stats