Optimization of Sample Preparation Methods on Formaldehyde Analysis in Meatball with Schryver’s Method

Febrina Amelia Saputri; Nur S.B. Rosli; Wiwiek Indriyati

doi:10.24198/ijpst.v6i2.18945

Optimization of Sample Preparation Methods on Formaldehyde Analysis in Meatball with Schryver’s Method

Febrina Amelia Saputri, Nur S.B. Rosli, Wiwiek Indriyati

Abstrak

Meatball is one of Indonesian’s favorite food. However, the fraudulent traders often add carcinogen compounds, formaldehyde to ensure the meatball is not easily rotten. The purpose of this study was to find out the best sample preparation method for formaldehyde analysis in the meatball. The preparation methods were the distillation, hot immersion, and cold immersion. Formaldehyde was then analyzed by Schryver’s method. UV-Vis spectrophotometer was used for quantitative analysis. The distillation method yielded the highest recovery (100.64%) compared to hot immersion (98.11%) and cold immersion (94.17%). The best method was used to test the meatball samples that have been collected around Jatinangor, Indonesia. The results of the qualitative analysis for five samples of meatball showed that two samples containing formaldehyde with the highest concentration of formaldehyde in the sample B2 (14.72ppm) and followed by B5 (8.77ppm).

Keywords : Cold immersion, distillation, formaldehyde, hot immersion, meatball, Schryver.

Teks Lengkap:

PDF (English)

Referensi

Checkoway H, Dell L, Boffeta P, Gallagher A, Crawford L Lees P, et al. Formaldehyde exposure and mortality Risks From Acute Myeloid Leukemia and Other Lymphohematopoietic Malignancies in the US National Cancer Institute Cohort Study of Workers in Formaldehyde Industries. Journal of Occupational and Environmental Medicine. 2015;57(7):785-794.

Swenberg JA, Moeller BC, Lu K, Rager JE, Fry R, Starr TB. Formaldehyde Carcinogenicity Research: 30 Years and Counting for Mode of Action, Epidemiology, and Cancer Risk Assessment. Toxicologic Pathology. 2013;41(2):181-189.

Zhang L, Tang X, Rothman N, Vermeulen R, Ji Z, Sehn, M, et al. Occupational Exposure to Formaldehyde, Hematotoxicity, and Leukemia-Specific Chromosome Changes in Cultured Myeloid Progenitor Cells. Cancer Epidemiology, Biomarkers and Prevention. 2010;19(1):80-88

Jayalakshmi K, Ravikumar H, Jaya N, Raju R. A silent killer in the laboratory – Formaldehyde: Review of effects and management. International Journal of Oral and Maxillofacial Pathology. 2011;2(2):13-19

International Agency for Research on Cancer. Monographs on the evaluation of carcinogenic risks to humans, vol. 88, formaldehyde, 2-butoxyethanol and 1-tert-butoxy-2-propanol. Lyon, France: IARC; 2004.

NTP 12th Report on Carcinogens. Formaldehyde. National Toxicology Program. 2011. PMID: 21822324

Committee on Diet, Nutrition, and Cancer. Diet, Nutrition, and Cancer. National Academy Press. Washington DC: National Academy of Sciences; 1982.

Minister of Health regulation No 033. Food Additives. 2012. Retrieved on May 21, 2018 from http://jdih.pom.go.id/produk/peraturan%20menteri/Permenkes%20ttg%20BTP.pdf

Saraswati, Tyas R. Research on the effect of formalin, diazepam, and alcoholic drinks on the body system. 2009. Retrieved on May 21, 2018 from Website: https://media.neliti.com/media/publications/129945-ID-pengaruh-formalin-diazepam-dan-minuman-b.pdf

Wicaksono. Analysis of formalin in fish and fresh shrimp with modified Schryver reagent (thesis). Depok, Indonesia: University of Indonesia; 2011.

Wulan. Identification of formalin in meatballs from meatball traders in Panukkang District, Makassar City (thesis). Makassar, Indonesia: Hasanudin University; 2015.

Safari M, Yamini Y, Tahmasebi E, Latifeh F. Extraction and preconcentration of formaldehyde in water by polypyrrole-coated magnetic nanoparticles and determination by high-performance liquid chromatography. Journal of Separation Science. 2015;38(19):3421-3427.

Tasooji M, Frazier CE. Simple milligram-scale extraction of formaldehyde from wood. ACS Sustainable Chemistry and Engineering. 2016;4(9):5041-5045.

Zhu Y, Peng Z, Wang M, Wang R, Rui L. Optimization of extraction procedure for formaldehyde assay in smoked meat products. Journal of Food Composition and Analysis. 2012;28(1):1-7.

Hill AA, Lipert RJ, Frirz JS, Porter MD. A rapid, simple method for determining formaldehyde in drinking water using colorimetric-solid phase extraction. Talanta. 2009;77(4):1405-1408.

Fatimah N, Nurhasnawati H, Zaki R. Formalin Identification in Wet Noodles using Schryver Reagent. Jurnal Ilmiah Manuntung. 2018;4(1):74-78.

Ermer J and Miller J.H.M. Method validation in pharmaceutical analysis: a guide to best practice. United States: John Wiley & Sons; 2005.

International Conference on Harmonization. Q2 Validation of analytical procedures : text and methodology international conference on harmonization of technical requirements for registration of pharmaceutical for human use. Canada: ICH Harmonized Tripartite Guideline; 2005.

Beitirevi. Optimization of phenylhydrazine HCl in Schryver reagent for analysis of formalin in wet noodles in Cimahi City with visible spectrophotometry (thesis). Cimahi, Indonesia: General Achmad Yani University; 2017.

National Agency of Drug and Food Control of Republic of Indonesia, Indonesia Pharmacopoeia. 5th ed. Jakarta: Ministry of Health; 2014.

Reuss W, Disteldorf A. O, Gamer A. H. Formaldehyde" in Ullmann's encyclopedia of industrial chemistry. Weinheim: Wiley-VCH; 2005.

Farid, M, Akyunul, J, and Anik, M. (2015). The temperature and time influence of immersion in water solvent against formaldehyde salted level belanak fish (Mugil cephalus). Alchemy Journal of Chemistry. 2015;4(II):121-126.

Purawisastra dan Sahara. The adsorption of formaldehyde by some foodstuffs and its elimination by soaking them in hot water. Penelitian Gizi Makanan. 2011;34(1):63-74.

Thavarajah R, Mudimbaimannar V. K, Elizabeth J, Rao U.K, Ranganathan K. Chemical and physical basics of routine formaldehyde fixation. Journal of Oral and Maxillofacial Pathology. 2012;16(3):400-405.

Elviani. (2013). Effect of temperature and duration of heating on protein levels contained in white swallow's nest (Collocalia Fuciphagus) (thesis). Bandung, Indonesia: Maranatha Christian University; 2013.

Herman, S, Maryati S, Yuanki, M. Analysis of Formalin in Fish and Shrimp from Muara Angke Market. Majalah Ilmu Kefarmasian. 2010;VII(3):16-31. Retrieved from: http://ejournal.undip.ac.id/index.php/sm/article/download/3279/2943

DOI: https://doi.org/10.24198/ijpst.v6i2.18945