Diuretic Effect of Combination of Watercress (Nasturtium officinale) and  Purslane (Portulaca oleraceae)

Afifah Bambang Sutjiatmo; Ni Luh Ade Yuliartati; Maulidya Yulianti; Suryani Suryani; Suci Nar Vikasari

doi:10.24198/ijpst.v10i3.36330

Diuretic Effect of Combination of Watercress (Nasturtium officinale) and Purslane (Portulaca oleraceae)

Afifah Bambang Sutjiatmo, Ni Luh Ade Yuliartati, Maulidya Yulianti, Suryani Suryani, Suci Nar Vikasari

Abstrak

Watercress (Nasturtium officinale) and purslane (Portulaca oleracea) are used to increase urination.
This preclinical study aims to prove the diuretic effect of a combination of watercress and purslane
extracts. Simplisia of watercress and purslane herbs mixed with various combinations A (1:9), B
(1:3) and C (1:1), then extracted in 50% ethanol. The animals were divided into five groups: control,
furosemide 3.6 mg/kgBW, A 38 mg/kgBW, B 28 mg/kgBW, and C 10 mg/kgBW. Diuretic assay was
carried out using the modified Lipschitz method with the parameters observed were cumulative urine
volume for 6 and 24 hours, and potassium levels in 24-hour urine. The results showed the onset of
diuretic effect of furosemide at 60 minutes, A at 150 minutes, B at 240 minutes and C at 90 minutes.
Percent effectiveness of the diuretic in the furosemide was 718%, A 212%, B 231%, and C 368% when
compared to the controls. All combinations of extracts increased sodium and potassium secretion when
compared to controls, but this effect was not as strong as furosemide. All combinations of watercress
and purslane herbs have a diuretic effect but weakly saluretic when compared to furosemide and the
combination that gives the best effect is combination C.

Kata Kunci

Combination, Diuretic, Nasturtium officinale, purslane, Portulaca oleracea, Watercress.

Teks Lengkap:

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Referensi

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DOI: https://doi.org/10.24198/ijpst.v10i3.36330