Phytochemical Screening And Antioxidant Activity Test of Lupun Root (Poikilospermum suaveolens (Blume) Merr) from South of Borneo

Lia Mardiana, Tiana Milanda, Yuni Elsa Hadisaputri, Anis Yohana Chaerunisaa

Abstrak


Lupun root is the local name for Poikilospermum suaveolens (Blume) Merr. in the Aranio region, South of Borneo, Indonesia. P.suaveolens is a medicinal plant traditionally used to treat various ailments and to enhance the body’s immune function. This study aimed to investigate the secondary metabolites and antioxidant capacity of the ethanol extract derived from the root of Lupun (P. suaveolens). Samples were collected from Aranio, South Borneo. Extraction was performed by maceration using 96% ethanol. The analysis included phytochemical screening and evaluation of antioxidant activity using the DPPH (2,2-diphenyl-1-picrylhydrazyl) assay measured by a UV-Vis spectrophotometer. Phytochemical screening revealed the presence of alkaloids, flavonoids, tannins, and phenolic compounds in the Lupun root extract. The antioxidant assay showed an IC50 value of 20.44 µg/mL, indicating strong antioxidant potential of the ethanol extract. These results highlight the plant’s promise as a candidate for pharmaceutical development.


Kata Kunci


Antioxidant; Phytochemical screening; Poikilospermum suaveolens

Teks Lengkap:

PDF

Referensi


Hartati, Habil M, Suryani AI. Analisis Fitokimia Ekstrak Tumbuhan Poikilospermum suaveolens Phytochemical analysis of the plant extract of Poikilospermum suaveolens. Published online 2020:365-370.

Wright CH. Hanopol. Published 2018. Accessed February 23, 2023. http://www.stuartxchange.org/ Hanopol.html

Fabroa J, Mindac P, Ann A, et al. The 4 International Scholars ’ Conference – Universitas Klabat Paper 151 Sciences. 2016;4(1):151. doi:https://doi.org/10.35974/ isc.v4i1.1856

Gema U A, Cesar G D. Pharmacophore Ethnomedicinal Plants Used By The Subanen Tribe In Two Villages In Ozamis City, Mindanao, Philippines. Pharmacophore. 2019;10(4):28-42.

Azliza Mad Anuar. A Comparison of Ethnobiological Knowledge Between the Mah Meri and Temuan Tribes in Selangor. Institut Sains Biologi, Fakulti Sains, Universiti Malaya, 2013; 2013.

Panyaphu K, Sirisa-ard P, Ubol PN, Nathakarnkitkul S. Phytochemical, antioxidant and antibacterial activities of medicinal plants in Thailand as post partum herbal bath. Phytopharmacology. 2012;2(1):92-105.

Qureshi R, Ghazanfar SA, Obied H, Vasileva V, Tariq MA. Ethnobotany: A Living Science for Alleviating Human Suffering. Evidence-Based Complement Altern Med. 2016;2016:9641692.

Subeki, Matsuura H, Yamasaki M, et al. Effects of Central Kalimantan plant extracts on intraerythrocytic Babesia gibsoni in culture. J Vet Med Sci. 2004;66(7):871-874. doi:10.1292/jvms.66.871

Gailea R, Ariffien Bratawinata A, Pitopang R, Kusuma I. The Use of Various Plant Types As Medicines by Local Community In The Enclave of The Lore-Lindu National Park of Central Sulawesi, Indonesia. Glob J Res Med Plants Indig Med. 2016;5(1):29-40.

Wibowo MIN., Kusuma A., Kulsum U, Diwanti RI., Dewi R. Tingkat Kepuasan Pasien Terhadap Kinerja Apoteker Puskesmas Di Tiga Kabupaten: Purbalingga, Banjarnegara, Cilacap Tahun 2015. J Pharm. 2016;14:46-70.

Salempa P, Pratiwi DE, Ramdhani. Toxicity Test of Mathanol Fraction of Mentawan (Poikilospermum suaveolens Blume Merr) Stem Which Has Potential as Anticancer. 2021;1899:1-5.

Fetalvero AA, Aclan JDM, Canoy GG, et al. Effect of Poikilospermum suaveolens (Hanopol) Leaf Extract on Non-Small Cell Lung Cancer Cell Lines. RINTED Philipp ISSN 2599-5456. Published online 2021:112.

Sirait TS, Arianto A, Dalimunthe A. Phytochemical Screening of Cinnamon Bark (Cinnamomum burmanii) (C. Ness & T. Ness) C. Ness ex Blume Ethanol Extract and Antioxidant Activity Test with DPPH (2,2-diphenyl1-picrylhydrazyl) Method. Int J Sci Technol Manag. 2023;4(1):254-259. doi:10.46729/ijstm.v4i1.739

Taufiq N, Sulfiani. Indonesian Journal of Chemical Research. Indones J Chem Res. 2023;1(11):43-48.

Sativum L, Putu N, Mahayani O, Satriyasa BK, Sumardika IW. Phytochemical Screening of Secondary Metabolites of 96 % Ethanol Extract of Coriander Seeds ( Coriandrum. 2023;6(3):1291-1295.

Baral R, Karki S, Neupane B, Koirala P, Baral S, Panta S. Phytochemical screening, Free radical scavenging, and In-vitro Anti-bacterial activity study of Chloroform, Acetone and Methanol extracts of selected medicinal plants of Nepal. Curr Perspect Med Aromat Plants. 2021;4:22-35.

Alkowni R, Jaradat N, Fares S. Total phenol, flavonoids, and tannin contents, antimicrobial, antioxidant, vital digestion enzymes inhibitory and cytotoxic activities of Verbascum fruticulosum. Eur J Integr Med. 2023;60:102256.

Molyneux P. The Use of the Stable Free Radical Diphenylpicryl-hydrazyl (DPPH) for Estimating Antioxidant Activity. Songklanakarin J Sci Technol. 2004;26:211-9.

Binuni R, Maarisit W, Saroinsong Y. Uji Aktivitas Antioksidan Ekstrak Daun Mangrove Sonneratia alba Dari Kecamatan Tagulandang , Sulawesi Utara Menggunakan Metode DPPH. Jurnal Biofarmasetikal Tropi. 2020;3(1):79-85.

Arum C, Cahya D, Harahap U, Nasution MP. Antioxidant Potential Of Ethanol Extract Of Kendondong Leaves (Spondias dulcis), Characterization And Examination Of Quercetin By TLC Method. International Journal of Science, Technology, and Management. 2023; 4(4):748-53.




DOI: https://doi.org/10.24198/ijpst.v12i2.51350

Refbacks

  • Saat ini tidak ada refbacks.


 Switch to English

Back to Top

View My Stats

Penerbit Universitas Padjadjaran

Jurnal ini terindeks di :

      

Creative Commons Attribution :

Creative Commons License
Indonesian Journal of Pharmaceutical Science and Technology by Universitas Padjadjaran is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Based on a work at http://jurnal.unpad.ac.id/ijpst/