Formulation and Antioxidant Activity Test of Purple Button Herb Ethanol Extract Peel-Off Mask
Abstrak
Purple button herb (Borreria laevis Lamk) contains secondary metabolites, including flavonoids, saponins, phenolics, tannins, and steroids, which have antioxidant activity. Facial masks include pharmaceutical preparations for cleaning, maintaining, and increasing attractiveness. This study aims to formulate a peel-off facial mask preparation from purple button herb extract (Borreria laevis Lamk), which is good and stable as an antioxidant. Ethanol extract from purple button herb was used as an active ingredient in the manufacture of peel-off gel masks with concentrations of 5% (F1), 10% (F2), and 15% (F3) with several physical evaluations including homogeneity, organoleptic (odor, color, shape), pH, drying time, viscosity and antioxidant activity tests carried out using the DPPH method. The results of the antioxidant activity test showed that the peel-off gel mask formula of ethanol extract of purple button herb at concentrations of 5%, 10%, and 15% met the requirements of a good and stable preparation with an IC50 value at a concentration of 5% (F1) of 149.82 µg/mL in the moderate category for antioxidant activity. Based on the test results, the purple button herb can be an antioxidant formulated for peel-off facial masks.
Kata Kunci
Teks Lengkap:
PDF (English)Referensi
Jain PK, Agrawal RK. Antioxidant and Free Radical Scavenging Properties of Developed Mono- and Polyherbal Formulations. Asian Journal of Experimental Sciences. 2008;22(3): 213– 20.
Draelos ZD. Antioxidants in skin care: Mechanisms of action and clinical efficacy. Journal of Cosmetic Dermatology. 2018;17(6):1172-1181.
Allemann IB, Baumann L. Antioxidants Used in Skin Care Formulations. Skin Therapy Letter. 2008;13(7): 5-9.
Lai-Cheong JE, McGrath JA. Structure and function of skin, hair and nails. Medicine. 2017; 45(6): 347-51.
Izzati M. Formulasi dan Uji Aktivitas Antioksidan Sediaan Masker Peel-off Ekstrak Etanol 50% Kulit Buah Manggis (Garsinia mangostana L.). [skripsi]. Jakarta: UIN Syarif Hidayatullah; 2014.
Lukita ME, Dhurhania CE, Andriani D. The formula development and antioxidant activity of peel-off gel mask from ethyl acetate fraction of bay leaf (Zyzygium polyanthum(Wight.) Walp.). Scientific Journal of Pharmacy. 2024;20(1):1-14
Yuliastri WO, Mahmudah R, Hamiru L, Fauziyah R, Ridwan BA, Salsyafirah W. Formulasi Sediaan Lip BalmKombinasi Ekstrak Etanol 96% Herba Kancing Ungu (Borreria laevis Lamk.) dan Ekstrak Etanol 96% Kulit Buah Manggis (Garcinia mangostana Linn.) Sebagai Antioksidan. Jurnal Mandala Pharmacon Indonesia. 2023;9(2):352-63.
Rubab M, Chelliah R, Oh, DH. Screening for Antioxidant Activity: Diphenylpicrylhydrazine (DPPH) Assay. In: Dharumadurai, D. (eds) Methods in Actinobacteriology. Springer Protocols Handbooks. Humana, New York, NY. 2022.
Kifli SA, Dewi C, Pusmarani J. Formulasi dan Uji Aktivitas Masker Gel Peel-Off Ekstrak Etanol Bunga Asoka (Ixora coccinea L.) sebagai Antioksidan. Jurnal Pharmacia Mandala Waluya. 2022;1(5):232-46.
Pebriani AA, Beandrade MZ. Formulation and Evaluation Of Gel Mask Peel Of Black Glutinous Rice Extract (Oryza sativa var glutinosa) and Green Tea (Camelia sinensis). Jurnal Mitra Kesehatan. 2021:1-11
Salwa S, Abdul KMB, Sulistyowati Y. Formulası Dan Evaluası Sedıaan Spray Gel Tabır Surya Fraksı Etıl Asetat Daun Cempedak (Artocarpus integer (Thunb.) Merr.) Dengan Kombınası Basıs Hpmc dan Karbopol 940. Jurnal Mahasiswa Kesehatan. 2020;2(1):12-23.
Sumule A, Pamudji G, Ikasari ED. Optimization of Aristoflex® AVC and Propylene Glycol in Turmeric (Curcuma domestica) Rhizome Extract Gel. Jurnal Farmasi Dan Ilmu Kefarmasian Indonesia. 2021;8(2):168-77
Indah I, Asri M, Suryanita S. Formulasi dan aktivitas antioksidan Sediaan Masker Gel Peel-Off Dari Ekstrak Etanol Buah Pepino (Solanum muricatum). Media Farmasi. 2021;17(2):97-107.
Lestari U, Farid F, Yuliawati. Physical Properties test peel off gel mask based of date palm seeds powder (Phoenix dactylifera) and olive oil. AIP Conference Proceeding. 2022; 2453(1): 022079
Ansel HC. Pengantar Bentuk Sediaan Farmasi, Edisi 4. Penerjemah Farida Ibrahim. Jakarta: Universitas Indonesia Press;1989.
Dantas MG, Reis SA, Damasceno CM, Rolim LA, Rolim-Neto PJ, Carvalho FO, et al. Development and Evaluation of Stability of a Gel Formulation Containing the Monoterpene Borneol. The Scientific World Journal. 2016 ;2016: 7394685
Taslim T, Pratama RH. Analisis Daya Antioksidan Senyawa Metabolit Sekunder Ekstrak Etanol Daun Surian (Toona sinensis(Juss) M.Roem). Jurnal Akademi Farmasi Prayoga. 2020; 5(2):19-28.
Rowe RC, Sheskey PJ, Owen. Handbook of Pharmaceutical Exipients. United Kingdom: Pharmacetical Press and American Pharmacist Association. 2009; 43.
Puttaraju S, Anil KV. 2015. Design and evaluation of topical gel formulations. International Journal of Research in Pharmaceutical Sciences, 6(3), 324-30.
Fox R.W, McDonald A.T, Pritchard PJ. (2015). Introduction to Fluid Mechanics. Wiley.
Patel DK, Nair A. Role of spreadability in transdermal drug delivery. Journal of Pharmaceutical and Scientific Innovation. 2013:2(4);67-71.
Desai S, Ghosh M. Evaluation of gel formulations: Characterization and assessment of drug release. International Journal of Drug Development and Research. 2016:8(1); 1-7.
Sawiji RT , Utariyani NW. Optimization of PVA and Glycerin Composition in Peel Off Gel Mask Dragon Fruit Skin Extract (Hylocereus lemairei) in Simplex Lattice Design. : Jurnal Ilmiah Mahaganesha.
;1(1): 18-26
Trisnaputri DR, Dewi C, Anisa SN, Isrul M, Fitriah WOI. Formulasi dan Uji Aktivitas Antioksidan Sediaan Masker Gel Peel-Off Ekstrak Etanol Daun Kelengkeng (Dimocarpus longan L.). Jurnal Mandala Pharmacon Indonesia. 2023;9(2):432-49.
Rahmasia, Sartini, Marzuki A. Pengaruh Bahan Tambahan Maltodextrin Dan Gom Arab Terhadap Kadar Total Polifenol Dari Ekstrak Teh Hijau (Camellia sinensis) Setelah Penyimpanan. Majalah Farmasi dan Farmakologi. 2019; 23(1):21-4.
Tonthawi M, Musfiroh I. Review: Peningkatan Stabilitas Vitamin C dalam Sediaan Kosmetika. Majalah Farmasetika. 2023;8(3):194-208.
Ambarwati R, Rustiani E. Formulasi dan Evaluasi Nanopartikel Ekstrak Biji Alpukat (Persea americana Mill) Dengan Polimer Plga. Majalah Farmasetika. 2022;7(4):305-13.
DOI: https://doi.org/10.24198/ijpst.v6i3.54210
Refbacks
- Saat ini tidak ada refbacks.
Switch to English Back to Top |
View My Stats Penerbit Universitas PadjadjaranJurnal ini terindeks di :Creative Commons Attribution :
Based on a work at http://jurnal.unpad.ac.id/ijpst/ |