Prescribing Pattern of Corticosteroid in Dermatologic Disorder at Tertiary Care Teaching Hospital in Western Indian

Zankrut J. Patel, Dhiren Patel, Jatin Patel, Sumit Patel

Abstract


Based on their potent immunosuppressive and anti-inflammatory properties, corticosteroids are essential for treating several skin disorders. Due to their lesser systemic toxicity, topical treatments are recommended. The use of corticosteroids in Indian dermatology practice, however, is not well documented. This study aims to analyze the prescribing patterns of corticosteroids for dermatologic disorders. In the outpatient dermatology department of GCS Hospital, Ahmedabad, a cross-sectional, observational study was conducted for six months, from March 2021 to August 2021. We looked at prevalent skin problems and prescribing patterns in 500 prescriptions. A descriptive statistical analysis was done following the compilation of all the data into Microsoft Office Excel. 169 patients (out of 500) receivedcorticosteroids. There were 53% men and 47% women, respectively. The Papulosquamous illness affected 33% of them. The average number of corticosteroids per prescription was 1.17. Out of 198 prescribed corticosteroids, 163 (82.32%) were topical formulations, and 35 (17.67%) were oral. Among the nine different corticosteroids prescribed, clobetasol was given to 29% of patients. Additionally, 39% of patients received a fixed-dose combination (FDC) of corticosteroids, with clobetasol and salicylic acid being the most commonly used FDC. The average cost of corticosteroids per prescription was 135.18 INR, ranging from 4 INR to 468 INR for 15 days of treatment. The mean cost of corticosteroids was significant compared to other concomitant drugs (P < 0.05). Topical corticosteroids were more commonly prescribed than oral ones, with psoriasis being the most common indication for topical corticosteroids. Clobetasol and mometasone were the most frequently used topical corticosteroids


Keywords


Corticosteroids; Dermatology; Prescribing pattern.

Full Text:

PDF

References


Mate VH, Gonarkar SB, Dhamani AM. Drug utilization for common skin diseases: an outpatient-based study. International Journal of Basic & Clinical Pharmacology 2019; 8:2604-8

Parvathy G, Sudha MJ, Pillai RT, Ramani PT. A study on the prescription pattern of antifungal drugs in the Dermatology Department of a tertiary care teaching hospital in Southern Kerala. International Journal of Basic & Clinical Pharmacology 2019;8:100-3.

Kushwaha A. Study the trends in dermatological disease and pattern of prescription in the dermatology department of a tertiary care hospital. World journal of pharmacy and pharmaceutical science. 2017; 6(8):1785-99.

Gupta R, Malhotra P. Prescribing pattern of corticosteroids among the dermatology inpatients in a tertiary care teaching hospital of north India - A retrospective, observational study. National Journal Physiology Pharmacy and Pharmacology 2018;8(2):158-162

Burkhart C, Morrell D, Goldsmith L. Dermatological Pharmacology. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s the Pharmacological basis of therapeutics. 12th ed. New Delhi: Mc Graw-Hill Publishers; 2011.1803-32.

Dr. Laxmi Bhagunde et al. Prescribing Pattern of Corticosteroids in Dermatology OPD in Tertiary Care Hospital JMSCR 2019;7(6)

Hengge UR, Ruziicka T, Schwartz RA, Cork MJ. Adverse effects of topical glucocorticosteroids. J Am Acad Dermatol. 2006;54(1):1-15; quiz 16-8.

World Health Organization (WHO). 10th revision of the International Statistical Classification of Diseases and Related Health Problems (ICD – 10). Chapter 12. L00-L99

Wahane PA, Jagtap RP, Ghongane BB. Evaluation of corticosteroid use pattern in steroid-responsive dermatological conditions. Int J Med Res Health Sci., 2016; 5(1): 82-86

S. Jain, P. Upadhyay, et al. A systemic review of prescription pattern monitoring studies and their effectiveness in promoting rational use of medicines. Perspectives in Clinical Research. 2015; 6(2):86-90. DOI: 10.4103/2229-3485.154005

Chetan Javsen. Rajesh Kumar Suman, Vithal G.Patil, Y A Deshmukh, To Study Prescription Pattern of Corticosteroids in Skin OPD in Tertiary Care Teaching Hospital. Asian Journal of Pharmacology and Toxicology 02 (04); 2014; 23-26.

Ankit P, Bharat G. Study of drug utilization pattern of glucocorticosteroids drugs with special emphasis on their immediate adverse effects in a tertiary care teaching rural hospital. Indian J Pharm Pract. 2010;3(4):18-23

Bylappa BK, Patil RT, Pillai RT. Drug prescribing pattern of topical corticosteroids in a dermatology unit of a tertiary-care hospital. Int J Med Sci Public Health. 2015;4(12):1702

Khan NA, Abid M, Maheswari KK, Kaviarasan PK, Mohanta GP. Antibiotic prescribing pattern in the department of dermatology of a teaching hospital in Tamil Nadu. Indian J Pharm Pract. 2010;3(3):18-21

Sarkar C, Das B, Sripathi H. Drug prescribing pattern in dermatology in a teaching hospital Western Nepal. Journal of Nepal Medical Association. 2001; 41:241-6.

Pathak AK, Kumar S, Kumar M, Mohan L, Dikshit H. Study of Drug Utilization Pattern for Skin Diseases in Dermatology OPD of an Indian Tertiary Care Hospital - A Prescription Survey. Journal of Clinical and Diagnostic Research. 2016; 10(2):FC01-FC




DOI: https://doi.org/10.15416/pcpr.v9i1.51833

Refbacks

  • There are currently no refbacks.


                                                                         
Pharmacology and Clinical Pharmacy Research is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
 
                                                                      VIEW VISITOR STATS