Isu Global Serius Infeksi Virus Nipah (NiV) Pada Manusia

Bilqis Na'ilah Almattin; Imam Adi Wicaksono

doi:10.24198/farmaka.v22i2.51865

Isu Global Serius Infeksi Virus Nipah (NiV) Pada Manusia

Bilqis Na'ilah Almattin, Imam Adi Wicaksono

Abstrak

Penyakit emerging zoonotik salah satunya yaitu penyakit virus Nipah (NiV). Virus Nipah merupakan infeksi yang disebabkan oleh Pteropodidae. Pteropodidae merupakan host alamiah dari penyakit virus Nipah (NiV). Virus Nipah telah menyebar di seluruh dunia, menyebabkan kematian di lima negara: Malaysia, India, Bangladesh, Singapura, dan Filipina, dengan 700 kasus pada manusia dan 407 kematian. Tidak ada laporan kasus di Indonesia, tetapi para peneliti menemukan kelelawar buah (geus Pteropus) yang terdapat di beberapa negara memiliki virus Nipah salah satunya Indonesia. Gejala awal infeksi virus Nipah yaitu sakit kepala, demam, mialgia, sakit tenggorokan, mual, muntah, batuk dan/atau ketidaknyamanan pernafasan. Saat ini, terapi yang digunakan untuk mengobati infeksi virus Nipah didasarkan pada pengobatan umum dan suportif, pengobatan simtomatik, dan menerapkan prosedur untuk mencegah penyebaran penyakit lebih lanjut. Maka dari itu, artikel ini bertujuan untuk menjelaskan studi mengenai penyakit virus Nipah untuk membuat orang tahu dan menjadi waspada terhadap virus Nipah yang telah terjadi di beberapa negara, terutama di Asia. Review artikel ini dibuat dengan metode komparatif disusun dari berbagai sumber jurnal penelitian mengenai virus Nipah (NiV). Data yang disajikan dalam tinjauan ini memperlihatkan bahwa sumber informasi yang tersedia mengenai virus Nipah sangat terbatas.

Kata kunci: penyakit infeksi, NiV, pteropodidae.

Teks Lengkap:

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Referensi

Aditi, & Shariff, M. 2019. Nipah virus infection: A review. Epidemiology and Infection, 147, 1–6. https://doi.org/10.1017/S0950268819000086

Anderson, D. E., Islam, A., Crameri, G., Todd, S., Islam, A., Khan, S. U., Foord, A., Rahman, M. Z., Mendenhall, I. H., Luby, S. P., Gurley, E. S., Daszak, P., Epstein, J. H., & Wang, L.-F. 2019. Isolation and Full-Genome Characterization of Nipah Viruses from Bats, Bangladesh. Emerging Infectious Diseases, 25(1), 166–170. https://doi.org/10.3201/eid2501.180267

Ang, B. S. P., Lim, T. C. C., & Wang, L. 2018. Nipah Virus Infection. Journal of Clinical Microbiology, 56(6). https://doi.org/10.1128/JCM.01875-17

Banerjee, S., Gupta, N., Kodan, P., Mittal, A., Ray, Y., Nischal, N., Soneja, M., Biswas, A., & Wig, N. 2019. Nipah virus disease: A rare and intractable disease. Intractable and Rare Diseases Research, 8(1), 1–8. https://doi.org/10.5582/irdr.2018.01130

Centers for Disease Control and Prevention. 2020. Signs & Symptoms. Signs & Symptoms. https://www.cdc.gov/vhf/nipah/symptoms/index.html

Centers for Disease Control and Prevention. 2022. Nipah Virus (NiV). Nipah Virus (NiV). https://www.cdc.gov/vhf/nipah/index.html#:~:text=Nipah virus is also known,Asia%2C primarily Bangladesh and India.

Devnath, P., Wajed, S., Chandra Das, R., Kar, S., Islam, I., & Masud, H. M. A. Al. 2022. The pathogenesis of Nipah virus: A review. Microbial Pathogenesis, 170(August), 105693. https://doi.org/10.1016/j.micpath.2022.105693

European Centre for Disease Prevention and Control. 2023. Factsheet on Nipah virus disease. Factsheet on Nipah Virus Disease. https://www.ecdc.europa.eu/en/infectious-disease-topics/z-disease-list/nipah-virus-disease/factsheet-nipah-virus-disease.

Hassan, M. Z., Sazzad, H. M. S., Luby, S. P., Sturm-Ramirez, K., Bhuiyan, M. U., Rahman, M. Z., Islam, M. M., Ströher, U., Sultana, S., Kafi, M. A. H., Daszak, P., Rahman, M., & Gurley, E. S. 2018. Nipah Virus Contamination of Hospital Surfaces during Outbreaks, Bangladesh, 2013-2014. Emerging Infectious Diseases, 24(1), 15–21. https://doi.org/10.3201/eid2401.161758

Hauser, N., Gushiken, A. C., Narayanan, S., Kottilil, S., & Chua, J. V. 2021. Evolution of Nipah Virus Infection: Past, Present, and Future Considerations. Tropical Medicine and Infectious Disease, 6(1). https://doi.org/10.3390/tropicalmed6010024

Kementerian Kesehatan Republik Indonesia. 2023. Surat Edaran Dirjen P2P tentang Kewaspadaan Terhadap Penyakit Virus Nipah. Kementerian Kesehatan RI, 4247608(021). https://www.kemkes.go.id/article/view/19093000001/penyakit-jantung-penyebab-kematian-terbanyak-ke-2-di-indonesia.html

Montgomery, J. M., Hossain, M. J., Gurley, E., Carroll, G. D. S., Croisier, A., Bertherat, E., Asgari, N., Formenty, P., Keeler, N., Comer, J., Bell, M. R., Akram, K., Molla, A. R., Zaman, K., Islam, M. R., Wagoner, K., Mills, J. N., Rollin, P. E., Ksiazek, T. G., & Breiman, R. F. 2008. Risk factors for Nipah virus encephalitis in Bangladesh. Emerging Infectious Diseases, 14(10), 1526–1532. https://doi.org/10.3201/eid1410.060507

Orosco, F. L. 2023. Advancing the frontiers: Revolutionary control and prevention paradigms against Nipah virus. Open Veterinary Journal, 13(9), 1056–1070. https://doi.org/10.5455/OVJ.2023.v13.i9.1

Rathish, B., & Vaishnani, K. 2023. Nipah Virus.

Sayed, A., Bottu, A., Qaisar, M., Mane, M. P., & Acharya, Y. 2019. Nipah virus: a narrative review of viral characteristics and epidemiological determinants. Public Health, 173, 97–104. https://doi.org/10.1016/j.puhe.2019.05.019

Sharma, V., Kaushik, S., Kumar, R., Yadav, J. P., & Kaushik, S. 2019. Emerging trends of Nipah virus: A review. Reviews in Medical Virology, 29(1), e2010. https://doi.org/10.1002/rmv.2010

Singh, R. K., Dhama, K., Chakraborty, S., Tiwari, R., Natesan, S., Khandia, R., Munjal, A., Vora, K. S., Latheef, S. K., Karthik, K., Singh Malik, Y., Singh, R., Chaicumpa, W., & Mourya, D. T. 2019. Nipah virus: epidemiology, pathology, immunobiology and advances in diagnosis, vaccine designing and control strategies - a comprehensive review. The Veterinary Quarterly, 39(1), 26–55. https://doi.org/10.1080/01652176.2019.1580827

Skowron, K., Bauza-Kaszewska, J., Grudlewska-Buda, K., Wiktorczyk-Kapischke, N., Zacharski, M., Bernaciak, Z., & Gospodarek-Komkowska, E. 2021. Nipah Virus-Another Threat From the World of Zoonotic Viruses. Frontiers in Microbiology, 12, 811157. https://doi.org/10.3389/fmicb.2021.811157

Skowron, K., Bauza-Kaszewska, J., Grudlewska-Buda, K., Wiktorczyk-Kapischke, N., Zacharski, M., Bernaciak, Z., & Gospodarek-Komkowska, E. 2022. Nipah Virus–Another Threat From the World of Zoonotic Viruses. Frontiers in Microbiology, 12(January). https://doi.org/10.3389/fmicb.2021.811157

Sun, B., Jia, L., Liang, B., Chen, Q., & Liu, D. 2018. Phylogeography, Transmission, and Viral Proteins of Nipah Virus. Virologica Sinica, 33(5), 385–393. https://doi.org/10.1007/s12250-018-0050-1

Thakur, N., & Bailey, D. 2019. Advances in diagnostics, vaccines and therapeutics for Nipah virus. Microbes and Infection, 21(7), 278–286. https://doi.org/10.1016/j.micinf.2019.02.002

Weatherman, S., Feldmann, H., & de Wit, E. 2018. Transmission of henipaviruses. Current Opinion in Virology, 28, 7–11. https://doi.org/10.1016/j.coviro.2017.09.004

Wongnak, P., Thanapongtharm, W., Kusakunniran, W., Karnjanapreechakorn, S., Sutassananon, K., Kalpravidh, W., Wongsathapornchai, K., & Wiratsudakul, A. 2020. A “what-if” scenario: Nipah virus attacks pig trade chains in Thailand. BMC Veterinary Research, 16(1), 300. https://doi.org/10.1186/s12917-020-02502-4

World Health Organization. 2009. Nipah virus infection. Nipah Virus Infection. https://www.who.int/publications/i/item/10665-205574.

World Health Organization. 2018. Nipah Virus. Nipah Virus. https://www.who.int/news-room/fact-sheets/detail/nipah-virus.

World Health Organization. 2021. R&D Blueprint and Nipah Virus. In R&D Blueprint and Nipah Virus. WHO. https://www.who.int/teams/blueprint/nipah

World Health Organization. 2023. Nipah Virus Infection - Bangladesh. Nipah Virus Infection - Bangladesh. https://www.who.int/emergencies/disease-outbreak-news/item/2023-DON442.

Yu, J., Lv, X., Yang, Z., Gao, S., Li, C., Cai, Y., & Li, J. 2018. The main risk factors of nipah disease and its risk analysis in China. Viruses, 10(10), 1–12. https://doi.org/10.3390/v10100572

DOI: https://doi.org/10.24198/farmaka.v22i2.51865

DOI (PDF): https://doi.org/10.24198/farmaka.v22i2.51865.g23486