Review: Formulasi Dan Evaluasi Sampo Berbagai Herbal Penyubur Rambut
Abstrak
Sampo adalah produk perawatan rambut paling umum yang digunakan masyarakat dengan bahan utama berupa surfaktan/deterjen. Salah satu tujuan penggunaan sampo adalah untuk mengobati masalah rambut rontok. Pengobatan rambut rontok menggunakan bahan sintetis serperti minoksidil dinilai belum cukup mengatasi rambut rontok karena menimbulkan efek samping yang tidak nyaman. Artikel ini bertujuan untuk membahas formulasi dan evaluasi sampo berbahan herbal perangsang pertumbuhan rambut disertai mekanisme herbal terhadap aktivitas pertumbuhan rambut. Metode yang digunakan adalah kajian pustaka secara elektronik berbagai jurnal internasional dan nasional yang diakses dari situs Google Scholar dan ScienceDirect terhadap jurnal internasional maupun nasional. Hasil kajian pustaka menunjukan perbedaan formula berpengaruh terhadap hasil evaluasi fisik 7 formula sampo herbal. Mekanisme herbal dalam menyuburkan rambut yaitu antioksidan, antiinflamasi, peningkat densitas rambut, pelebar folikel rambut, perpanjang fase anagen, sebagai nutrisi folikel rambut, metabolisme androgen, inhibisi PAK1 (P21-activated kinases) dan induksi reaksi immunologi. Dari artikel ini dapat disimpulkan bahwa formula terbaik sampo adalah formula sampo ekstrak licorice dengan kandungan kombinasi surfaktan dan hasil evaluasi sesuai dengan syarat parameter evaluasi yang telah ditetapkan. Dalam perangsangan pertumbuhan rambut, herbal yang dijadikan sebagai bahan utama sampo memiliki mekanisme yang beragam.
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