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Artikel Review: Potensi Kolagen sebagai Bahan Aktif Sediaan Farmasi
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Kolagen merupakan protein yang terdapat di kulit, tendon, tulang rawan, dan organ dengan kandungan sekitar 30% atau lebih dari protein total. Saat ini, kolagen telah ditemukan mempunyai 29 jenis dengan struktur dan urutan asam amino yang berbeda. Kolagen mempunyai karakteristik fisikokimia yang baik yaitu bersifat biokompatibel, biodegradable, antigenisitas yang rendah, dan nontoksik dengan berbagai aktivitas yang dapat mendukungnya sebagai sediaan farmasi. Review artikel dilakukan untuk mengumpulkan informasi tentang kolagen yang memiliki berbagai aktivitas sebagai sediaan farmasi. Artikel dikumpulkan dari 107 artikel penelitian. Artikel ini membahas tentang potensi kolagen sebagai sediaan farmasi untuk kesehatan. Hasil yang didapatkan adalah kolagen memiliki banyak peran dalam tubuh sehingga memiliki banyak aktivitas untuk kesehatan, terutama sebagai antiinflamasi, menyembuhkan luka, kondroprotektif, pertumbuhan dan homeostasis kulit, tendon, tulang, otot, dan saraf, dan antikanker. Kolagen sangat mempengaruhi tubuh dan dapat dijadikan sediaan farmasi sebagai suplemen, kosmetik, ataupun scaffolding material untuk kesehatan.
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