Essential Oil Composition, Antioxidant and Antibacterial Activities of Nutmeg (Myristica fragrans Houtt) from Garut West Java

Diki Prayugo Wibowo; Yessi Febriana; Hesti Riasari; Diah Lia Auilifa

doi:10.24198/ijpst.v5i3.16030

Essential Oil Composition, Antioxidant and Antibacterial Activities of Nutmeg (Myristica fragrans Houtt) from Garut West Java

Diki Prayugo Wibowo, Yessi Febriana, Hesti Riasari, Diah Lia Auilifa

Abstrak

West Java is rich in essential oil-producing plants, essential oils known to be responsible for some pharmacological activities among its antioxidant and antimicrobial. This research aims to know antimicrobial, antioxidant activity and identify the components of a compound essential oil of nutmeg (Myristica fragrans Houtt.). Components chemistry identified with GC-MS (Gas Chromatography-Mass pectrometer). Antioxidant activity measured by using the DPPH method (2 2-diphenyl-1-picrylhydrazyl) at 516 λ wavelength absorbance. Antimicrobial activity determined Minimum Inhibitory Concentrations (MIC) and Minimum Bactericidal Concentrations (MBC) using microdilution method. The result of GC-MS showed the highest component on nutmeg containing 22.22% myristicin. The antioxidant test showed nutmeg had IC₅₀ at 3,16%, essential oil showed antibacterial activity against Gram positive and Gram negative bacteria. Minimum inhibitory concentrations of essential oils range from 0.313% to 10%. The content of essential oils of nutmeg plants that grow in the area of West Java Garut can be used to overcome the problems of antioxidants and antimicrobial.

Key words: Antioxidant, Antibacterial, Pala (Myristica fragrans Houtt), Chemical Composition.

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Referensi

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DOI: https://doi.org/10.24198/ijpst.v5i3.16030