Antioxidant Ability of the 2% Indonesian Mount Lawu Propolis Ear Drops

Hadi Sudrajad; Made Setiamika; Sarwastuti Hendradewi; Novi Primadewi; Putu Wijaya Kandhi; Dewi Pratiwi; Aningdita Kesumo; Primadita Asis Pratiwi

doi:10.24198/ijpst.v12i1.53208

Antioxidant Ability of the 2% Indonesian Mount Lawu Propolis Ear Drops

Hadi Sudrajad, Made Setiamika, Sarwastuti Hendradewi, Novi Primadewi, Putu Wijaya Kandhi, Dewi Pratiwi, Aningdita Kesumo, Primadita Asis Pratiwi

Abstrak

Propolis ear drops are natural antioxidants that have been developed for various health purposes. There are many types of propolis ear drops available today, including the Indonesian Mount Lawu Propolis ear drop (IMLPED). Indonesian Mount Lawu Propolis ear drop is proven to contain many antioxidant substances such as flavonoids, phenolic acids, caffeic acid pethyl ester, and quercetin. However, to date, no study has assessed the antioxidant activity of IMLPED, especially the 2% IMLPED. This study aims to assess the antioxidant activity of the 2% IMLPED. This is an in vitro study to assess the antioxidant activity of the 2% IMLPED with 2,2-Diphenyl-1-Picrylhydrazyl (DPPH) method based on the inhibitory concentration at 50% (IC₅₀) value. The IC₅₀ represents the concentration required to reduce 50% of the free radicals. The result of this study showed that the IC₅₀ value of the 2% IMLPED is 30.71 µg/mL. Based on the IC₅₀ value, the 2% IMLPED formula exhibits a robust antioxidant effect. The implications of this revelation establish IMLPED as a promising candidate in combating oxidative stress.

Kata Kunci

Indonesia mount lawu propolis, ear drops, antioxidants, IC50.

Teks Lengkap:

PDF (English)

Referensi

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DOI: https://doi.org/10.24198/ijpst.v12i1.53208