ODONTOGENIC INFECTION AS A HIDDEN ROUTE OF GENERALIZED TETANUS IN THE INTENSIVE CARE UNIT: CASE REPORT
Abstract
Tetanus, an infection caused by Clostridium tetani, remains a global health concern due to its high fatality, morbidity, and mortality rates. Although the spores of this bacterium are commonly found in soil and animal waste, contamination of the oral cavity due to poor oral hygiene and inadequate dental care also presents a significant risk. The aim of this study was to describe the role of dental infection in the incidence of tetanus in the intensive care unit. This study used descriptive study design with case report method. A 67-year-old male patient was admitted for 38 days to the intensive care unit of a government hospital in Bandung due to grade III generalized tetanus, with Ablett grade IV classification and Tetanus Severity Score (TSS) of 7. The patient had a history of stab wounds from wood and multiple plaque (+) in the oral cavity due to poor oral hygiene and had a habit of cleaning teeth using sticks that were not clean and not in accordance with recommended dental care tools.. History of tetanus vaccine with incomplete dose. During treatment, the patient required mechanical ventilator assistance with CPAP-PS mode. Conclusion of this research that the route of entry for tetanus-causing bacteria can be through wounds, including wounds in the oral cavity that often go unnoticed. Therefore, it is very important to maintain oral hygiene through the application of proper oral hygiene and eliminate the habit of cleaning teeth with dirty tools.
Full Text:
PDFReferences
Akbar, M., Ruslin, M., Yusuf, A. S. H., Boffano, P., Tomihara, K., & Forouzanfar, T. (2022). Unusual generalized tetanus evolving from odontogenic infection: A case report and review of recent literature. Heliyon, 8(9), e10810.https://doi.org/10.1016/j.heliyon.2022.e10810
Amaliah, N., & Wardhany, I. I. (2024). Dentist’S Role in Collaborative Management of Tetanus Patient (Peran Kolaborasi Dokter Gigi Dalam Manajemen Pasien Tetanus). Jhds, 2024(03), 303. https://doi.org/10.54052/jhds.Article
Aprilia, C., Prasanty, E., Santoso, G. A., & Choiriyah, N. (2024). From Tooth To Tetanus : A Case Report On Tetanus Following An Odontogenic Infection. 43–46. https://doi.org/10.21776/ub.jphv.2024.005.02.05
Bassey, G. O., Anyanechi, C. E., & Osunde, O. D. (2018). Tetanus infection following dental extraction: A case report. Cross River Journal of Medicine , 2(1), 13–16.
Baviskar, P. S., Ahuja, S. A., Natarajan, S., & Bagchi, P. R. (2021). Tetanus of suspected dental causality. Journal of Stomatology, Oral and Maxillofacial Surgery, 122(1), 115–118. https://doi.org/10.1016/j.jormas.2020.05.004
Behrens, H., Ochmann, S., Dadonaite, B., & Roser, M. (2024). Tetanus. Retrieved from Our World in Data website: https://ourworldindata.org/tetanus
Centers for Disease Control and Prevention (CDC). (2025). Tetanus Surveillance and Trends. Retrieved from https://www.cdc.gov/tetanus/php/surveillance/index.html
Darraj, M., Stone, J., Keynan, Y., Thompson, K., & Snider, C. (2017). A case of tetanus secondary to an odontogenic infection. Canadian Journal of Emergency Medicine, 19(6), 497–499. https://doi.org/10.1017/cem.2016.390
Dipalma, G., Laforgia, A., Ciccarese, D., Marotti, P., Inchingolo, A. D., Inchingolo, F., … Inchingolo, A. M. (2024). ODONTOGENIC INFECTIONS : RECOMMENDATIONS AND BEST PRACTICES. 8(1), 3–13.
Harum, A. (2014). Dental Caries as a Risk Factor of Tetanus. J Medula Unila, 3(2), 8–15.
Lertpimonchai, A., Rattanasiri, S., Arj-Ong Vallibhakara, S., Attia, J., & Thakkinstian, A. (2017). The association between oral hygiene and periodontitis: a systematic review and meta-analysis. International Dental Journal, 67(6), 332–343. https://doi.org/10.1111/idj.12317
Mcelaney, P., Iyanaga, M., Monks, S., & Michelson, E. (2019). The Quick and Dirty: A Tetanus Case Report. Clinical Practice and Cases in Emergency Medicine, 3(1), 55–58. https://doi.org/10.5811/cpcem.2019.1.41301
Meregildo-Rodriguez, E. D., Asmat-Rubio, M. G., & Vásquez-Tirado, G. A. (2023). Tetanus secondary to oral and odontogenic infections: a case report and systematic literature review. Infezioni in Medicina, 31(1), 93–102. https://doi.org/10.53854/liim-3101-13
Mubaraq, S. El, Saputra, R. C., & Prihatiyanto, M. A. (2024). Laporan Kasus Infeksi Tetanus Derajat 4: Dampak Karies Gogo dan Perjalanan Penyakit Yang Cepat. Proceeding of Thalamus 2024, 607–614.
Nakajima, M., Aso, S., Matsui, H., Fushimi, K., & Yasunaga, H. (2018). Clinical features and outcomes of tetanus: Analysis using a National Inpatient Database in Japan. Journal of Critical Care, 44, 388–391. https://doi.org/10.1016/j.jcrc.2017.12.025
Putri, S. R. (2020). Pencegahan Tetanus. Jurnal Penelitian Perawat Profesional, 2(4), 443–450.
Robinson, I. B., & Laskin, D. M. (1957). Tetanus of Oral Origin. Oral Medicine. https://doi.org/https://doi.org/10.1016/0030-4220(57)90113-5
Setiawati, T., Robbihi, H. I., & Dewi, T. K. (2022). Hubungan Usia Dan Jenis Kelamin Dengan Periodontitis Pada Lansia Puskesmas Pabuarantumpeng Tangerang. JDHT Journal of Dental Hygiene and Therapy, 3(1), 43–48. https://doi.org/10.36082/jdht.v3i1.309
Surya, R. (2016). Pengaruh Infeksi Malaria Vivax pada Kehamilan. Cermin Dunia Kedokteran, 43(12), 920–923. Retrieved from http://download.garuda.kemdikbud.go.id/article.php?article=2468366%5C&val=23521%5C&title=Pengaruh Infeksi Malaria Vivax pada Kehamilan
Tejpratap, Tiwari, Moro, P. L., & Acosta, A. M. (2021). Chapter 21 Tetanus. In Epidemiology and Prevention of Vaccine-Preventable Diseases (14TH Editi). USA: US Department of Health and Human Services, Centers for Disease Control and Prevention. Retrieved from https://www.cdc.gov/pinkbook/hcp/table-of-contents/chapter-21-tetanus.html?CDC_AAref_Val=https://www.cdc.gov/vaccines/pubs/pinkbook/tetanus.html
Thwaites, C. L., & Loan, H. T. (2015). Eradication of tetanus. British Medical Bulletin, 116(1), 69–77. https://doi.org/10.1093/bmb/ldv044
Ulfa, M., & Husna, N. A. (2020). A case report of generalized tetanus in a 42-year-old man with dental infection. Journal of Basic and Clinical Physiology and Pharmacology, 30(6), 1–4. https://doi.org/10.1515/jbcpp-2019-0243
Wati, S., & Syahrul. (2018). Tata Laksana Tetanus Generalisata Dengan Karies Gigi (Laporan Kasus). Cakradonya Dental Journal, 10(2), 86–95. https://doi.org/10.24815/cdj.v10i2.11707
WHO. (2018). Non-neonatal Tetanus: Vaccine Preventable Diseases Surveillance Standards. https://doi.org/10.1136/bmj.1.5333.818-a
WHO. (2020). Indonesia: Tetanus. Retrieved from world health rankings website: https://www.worldlifeexpectancy.com/indonesia-tetanus
DOI: https://doi.org/10.24198/pacnj.v4i2.64614
Refbacks
- There are currently no refbacks.
Copyright (c) 2025 Padjadjaran Acute Care Nursing Journal

.png)











This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.